Evaluation of p53 and soluble Fas ligand (sFasL) serum level concentration as indicators of apoptosis in serum of patients with benign and malignant primary follicular …

K Kołomecki, P Maciaszczyk, H Stępień… - Endokrynologia …, 2006 - journals.viamedica.pl
Introduction: Apoptosis (programmed cell death) is the best described mode of physiological
cell death. During embryonal development and morphogenesis, apoptosis may be induced
by two pathways. The first is external protein signal originating from other cell-also named
as" death signal". Another one is specific cell reaction for external stress factors. Blood
concentration of proteins regulating both pathways of apoptosis may be useful in early
diagnosis and staging of thyroid tumors. The aim of study was evaluation of p53 and sFasL …
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